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INSTACOAT E-SERIES New

READY-TO-USE FILM COATING

PHARMA ACRYLIC POLYMERS

COOLING COMPOUNDS

NEUTRAL SPHERES

R & D COATER

FILM COATING - NUTRACEUTICALS

CONTROLLED RELEASE PRODUCTS

BRANDING SOLUTIONS

Espheres SIO2

Ecospheres logo

ESPHERES SIO2 (Silicon Dioxide Spheres)

Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPS technology.

Definition:

  • ESPHERES SIO2 contains not more than 75% of Silicon Dioxide, calculated on the dried basis
  • Colloidal Silicon Dioxide Complying with Ph.Eur., USP/NF and JP
  • Produced in accordance with cGMP

Composition:

  • Colloidal Silicon Dioxide

Features:

  • White Coloured, hard brittle
  • Low friability/Solubility
  • Free flowing spheres
  • High standard
  • Uniform sphere size 
  • Anti-caking agent
  • Uniform & Consistent Loading

General and microbiological information:

Loss on drying – NMT 10%
< 100 cfu/g; No Pathogens  
pH – 4 to 7.5
Residue on ignition: – 52.5-87.5% 

Re-evaluation Date - 36 months from the date of manufacture.

Applications:

  • Adapted for controlled release or Sustained release formulations to produce spherical granules or pellets which have the most suitable size and dissolution profile.
  • Suitable for highly soluble active pharmaceutical ingredients.

Particle Size (U.S. Standard Sieve) and specifications:

Product
12/14
14/16
16/18
18/20
20/25
25/30
30/35
35/40
40/60
ESPHERES SIO2 bullet bullet bullet bullet bullet bullet bullet bullet bullet
  • All intermediates ESPHERES are available on request.
  • Not less than 90% of it passes the coarser sieve size stated in the labeling available on request.
  • Not more than 10% passes the finer sieve size stated in the labeling. All of it passes the next coarser sieve listed in test procedure.

For more details about ESPHERES™ products, please contact us at info@idealcures.co.in