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INSTACOAT E-SERIES New

READY-TO-USE FILM COATING

PHARMA ACRYLIC POLYMERS

COOLING COMPOUNDS

NEUTRAL SPHERES

R & D COATER

FILM COATING - NUTRACEUTICALS

CONTROLLED RELEASE PRODUCTS

BRANDING SOLUTIONS

TERMS & CONDITIONS FOR SALE

Instacoat Spectrum

 

controlled release products

controlled release products


Instamodel logo

AN EXPERT SYSTEM FOR DRUG DELIVERY SOLUTION.

With the evolution of pharmaceutical technology and understanding of human physiology and pathology, the need was to felt to control the time, site and rate of drug delivery. This gave rise to the so called Drug Delivery Systems. Modified Release Drug Delivery Systems form the major part of Drug Delivery Market.

With its background and technical know-how Ideal Cures has developed an expert system called ‘Instamodel’ Extended Release system based on predictive modelling for HPMC matrix tablets.

CONCEPT OF INSTAMODEL EXTENDED RELEASE SYSTEM:

The success of HPMC matrix tablet formulation depends upon the right selection of HPMC grade, diluents, their ratios and tablet geometry. Ideal Cures has done extensive work in this field using new techniques such as fractal geometry, actual experimentation and interpretation of the results so obtained. This has led to development of a sound technical database. Based on this database, Ideal Cures has developed a predictive computer model that could generate the exact blend of polymer and diluents required to achieve the target release profile. The user runs the trial at his/her end using the Instamodel blend and the API. In 80% of the cases, it was found that the developed blend and the formula met the target. In remaining cases, some fine tuning was required which was done simply by increasing or decreasing the ratio of the Instamodel blend to the drug.

THE INSTAMODEL SERVICE IS AVAILABLE IN TWO FORMS

1. INSTAMODEL BLEND

This is a proprietary, optimized blend of hypromellose polymers and tablet diluents. The start-up formula is generated by the INSTAMODEL predictive modeling system and supplied to the customer. The formulator is required to add the drug and processing aids and compress the blend.

2. INSTAMODEL ER

This is a proprietary, optimized blend of hypromellose polymers. This blend is developed using INSTAMODEL predictive modeling system. The formulator has to add suitable diluents and processing aids along with API to this blend and compress the matrix.

MECHANISM OF DRUG RELEASE FROM HYPROMELLOSE MATRICES:

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SALIENT FEATURES OF INSTAMODEL SERVICE:

  • Designed to provide starting formulations to customers for hydrophilic matrix systems based on Hypromellose polymers
  • Accessed through www.idealcures.co.in or your local Ideal Cures contact
  • Increases speed to market
  • Improves efficiency and productivity
  • Reduces number of trials required to reach the final formulation
  • Based on predictive modeling system
  • Software generated formulations with predicted release profile
  • Backed by strong technical support from Ideal Cures

WORK FLOW OF INSTAMODEL - EXTENDED RELEASE SYSTEM:

 work flow

APPLICATION EXAMPLES OF INSTAMODEL SERVICE:

  • CNS DRUGS like Divalproex sodium, Carbamazepine, Lithium carbonate, Phenytoin sodium, Alprazolam, Risperidone
  • CVS DRUGS like Metoprolol succinate, Nifedipine, Amityrptylline, Propranolol hydrochloride, Felodipine,  Diltiazem,Isosorbidemononitrate Verapamil, Indapamide
  • ANTIDIABETIC DRUGS like Metformin hydrochloride, combinations of metformin and other anti-diabetics, Gliclazide,
  • ANALGESIC DRUGS like Diclofenac sodium,Aceclofenac, Tramadol hydrochloride,  Paracetamol, Naproxen, Ketoprofen, Ibuprofen
  • ANTIBACTERIAL DRUGS like Ciprofloxacin hydrochloride, Naldixic acid, Ofloxacin, Clarithromycin, Metronidazole, Nitrofurantoin
  • ANTI-ASTHMATIC DRUGS likePseudoephedrine hydrochloride, Terbutaline sulfate, Theophylline
  • Others Ascorbic acid, Nicotinic acid, Ferrous sulfate.

More drugs under each category are available under INSTAMODEL Extended Release System.